American Airlines flight AA 5643: Multiple routes

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Thu 05:00 Houston Hobby (HOU) 06:13 Dallas Fort Worth (DFW)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:13 Operates only on 2025-06-05
Daily 05:06 Syracuse (SYR) 06:09 Philadelphia (PHL) F
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:03 Effective 2025-06-06 through 2025-07-04
Daily 06:22 Syracuse (SYR) 07:34 Philadelphia (PHL) F
AA 5643 Non-stop Canadair CRJ 700 (CR7) 1:12 Effective 2025-09-03 through 2025-10-05
Daily 06:27 Syracuse (SYR) 07:40 Philadelphia (PHL) F
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:13 Effective 2025-08-06 through 2025-09-02
Daily 11:05 Charlotte (CLT) 12:23 Knoxville (TYS)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:18 Effective 2025-10-06 through 2025-11-01
Daily 11:05 Charlotte (CLT) 12:36 Knoxville (TYS)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:31 Effective 2025-11-02 through 2025-12-02
Daily 11:05 Charlotte (CLT) 12:16 Knoxville (TYS)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:11 Effective from 2026-02-12
Sat 11:10 Charlotte (CLT) 12:29 Knoxville (TYS)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:19 Valid until 2025-05-03
Daily 12:37 Knoxville (TYS) 13:55 Charlotte (CLT)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:18 Effective from 2026-02-12
Daily 12:41 Knoxville (TYS) 13:55 Charlotte (CLT)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:14 Effective 2025-10-06 through 2025-11-01
Sat 13:00 Knoxville (TYS) 14:22 Charlotte (CLT)
AA 5643 Non-stop Canadair CRJ 900 (CR9) 1:22 Valid until 2025-05-03
Mon-Sat 19:59 Ronald Reagan Washington (DCA) 2 21:12 Birmingham (BHM)
AA 5643 Non-stop Canadair CRJ 700 (CR7) 2:13 Effective 2025-07-05 through 2025-08-05
Sun 21:39 Ronald Reagan Washington (DCA) 2 22:41 Birmingham (BHM)
AA 5643 Non-stop Canadair CRJ 700 (CR7) 2:02 Effective 2025-07-06 through 2025-08-03
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This flight number is listed as serving the following routes:


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American Airlines flight AA 5643: Multiple routes
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
American Airlines AA5643
05:00
Houston Hobby (HOU)

06:13
Dallas Fort Worth (DFW)
Operates only on 2025-06-05
Mon
-
Tue
-
Wed
-
Thu
Fri
-
Sat
-
Sun
-
Duration: 1:13, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
05:06
Syracuse (SYR)

06:09
Philadelphia (PHL) F
Effective 2025-06-06 through 2025-07-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:03, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
06:22
Syracuse (SYR)

07:34
Philadelphia (PHL) F
Effective 2025-09-03 through 2025-10-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:12, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5643
06:27
Syracuse (SYR)

07:40
Philadelphia (PHL) F
Effective 2025-08-06 through 2025-09-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:13, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
11:05
Charlotte (CLT)

12:23
Knoxville (TYS)
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:18, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
11:05
Charlotte (CLT)

12:36
Knoxville (TYS)
Effective 2025-11-02 through 2025-12-02
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:31, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
11:05
Charlotte (CLT)

12:16
Knoxville (TYS)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:11, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
11:10
Charlotte (CLT)

12:29
Knoxville (TYS)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:19, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
12:37
Knoxville (TYS)

13:55
Charlotte (CLT)
Effective from 2026-02-12
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:18, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
12:41
Knoxville (TYS)

13:55
Charlotte (CLT)
Effective 2025-10-06 through 2025-11-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 1:14, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
13:00
Knoxville (TYS)

14:22
Charlotte (CLT)
Valid until 2025-05-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
Sun
-
Duration: 1:22, non-stop
Canadair CRJ 900 (CR9)
American Airlines AA5643
19:59
Ronald Reagan Washington (DCA) 2

21:12
Birmingham (BHM)
Effective 2025-07-05 through 2025-08-05
Mon
Tue
Wed
Thu
Fri
Sat
Sun
-
Duration: 2:13, non-stop
Canadair CRJ 700 (CR7)
American Airlines AA5643
21:39
Ronald Reagan Washington (DCA) 2

22:41
Birmingham (BHM)
Effective 2025-07-06 through 2025-08-03
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:02, non-stop
Canadair CRJ 700 (CR7)
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This flight number is listed as serving the following routes:
  • Houston Hobby (HOU) - Dallas Fort Worth (DFW)
  • Knoxville (TYS) - Charlotte (CLT)
  • Ronald Reagan Washington (DCA) - Birmingham (BHM)
  • Syracuse (SYR) - Philadelphia (PHL)
All American Airlines flights
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