All airlines flying from Panama City Tocumen (PTY) to Guayaquil (GYE).

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Select flight date:
FLIGHT SCHEDULE
Direct Flights:
Mon,Fri 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective 2025-05-12 through 2025-05-16
Mon-Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2025-05-17 through 2025-05-31
Fri 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective 2025-05-23 through 2025-05-30
Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:13 Operates only on 2025-06-01
Daily 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2025-06-02 through 2025-06-08
Mon,Fri 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective 2025-06-09 through 2025-06-23
Tue-Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2025-06-10 through 2025-06-26
Fri-Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2025-06-27 through 2025-06-29
Mon 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Operates only on 2025-06-30
Mon,Tue,Thu-Sun 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-07-01 through 2025-07-08
Wed 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:15 Operates only on 2025-07-02
Daily 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-07-09 through 2025-08-10
Mon,Wed 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:15 Effective 2025-08-11 through 2025-08-13
Mon,Tue,Thu-Sun 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-08-12 through 2025-08-21
Mon,Wed,Fri 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:15 Effective 2025-08-20 through 2025-08-27
Tue,Thu-Sun 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-08-23 through 2025-08-31
Daily 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-09-01 through 2025-10-07
Wed 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:15 Operates only on 2025-10-08
Daily 15:19 Panama City Tocumen (PTY) 17:34 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-10-09 through 2025-10-25
Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Operates only on 2025-10-26
Daily 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2025-10-27 through 2025-11-04
Wed,Thu,Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2025-11-05 through 2025-11-12
Mon,Tue,Thu-Sat 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2025-11-07 through 2025-11-13
Wed,Fri,Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2025-11-14 through 2025-11-19
Mon,Tue,Thu-Sat 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2025-11-15 through 2025-12-22
Wed,Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2025-11-23 through 2025-12-24
Tue 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 8 (7M8) 2:17 Operates only on 2025-12-23
Mon,Tue,Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2025-12-25 through 2026-01-08
Fri 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:17 Effective 2025-12-26 through 2026-01-23
Wed 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2025-12-31 through 2026-01-07
Wed,Sat 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2026-01-10 through 2026-01-14
Mon,Tue,Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2026-01-11 through 2026-01-29
Wed 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:17 Effective 2026-01-21 through 2026-01-28
Fri,Sat 15:19 Panama City Tocumen (PTY) 17:36 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:17 Effective 2026-01-30 through 2026-01-31
Mon,Tue,Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2026-02-01 through 2026-02-19
Wed 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-700 (73G) 2:13 Effective from 2026-02-04
Fri 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective 2026-02-06 through 2026-02-13
Mon,Tue,Thu-Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective 2026-02-20 through 2026-02-26
Fri 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective from 2026-02-27
Mon,Tue,Thu,Sat,Sun 15:19 Panama City Tocumen (PTY) 17:32 Guayaquil (GYE)
Copa Airlines CM 378 Non-stop Boeing 737-800 (738) 2:13 Effective from 2026-02-28
Non-Direct Flights:
Mon,Fri,Sun 11:05 Panama City Tocumen (PTY) 1 17:20 Guayaquil (GYE)
Avianca AV 8383 1-stop Airbus A320 (320) 6:15 Valid until 2025-06-01
Mon,Fri,Sun 11:25 Panama City Tocumen (PTY) 1 17:15 Guayaquil (GYE)
Avianca AV 8383 1-stop Airbus A320 (320) 5:50 Effective from 2025-10-26
Direct Codeshare Flights:
Daily 18:18 Panama City Tocumen (PTY) 20:35 Guayaquil (GYE)
KLM KL 3009 Non-stop Boeing 737 MAX 9 (7M9) 2:17 Effective 2025-10-26 through 2026-01-31
Codeshare flight, operated by Copa Airlines.(CM 213)
Daily 18:20 Panama City Tocumen (PTY) 20:33 Guayaquil (GYE)
KLM KL 3009 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Valid until 2025-06-30
Codeshare flight, operated by Copa Airlines.(CM 213)
Daily 18:20 Panama City Tocumen (PTY) 20:35 Guayaquil (GYE)
KLM KL 3009 Non-stop Boeing 737 MAX 9 (7M9) 2:15 Effective 2025-07-01 through 2025-10-25
Codeshare flight, operated by Copa Airlines.(CM 213)
Daily 18:20 Panama City Tocumen (PTY) 20:33 Guayaquil (GYE)
KLM KL 3009 Non-stop Boeing 737 MAX 9 (7M9) 2:13 Effective from 2026-02-01
Codeshare flight, operated by Copa Airlines.(CM 213)
Daily 21:24 Panama City Tocumen (PTY) 23:37 Guayaquil (GYE)
KLM KL 3012 Non-stop Boeing 737-800 (738) 2:13 Valid until 2025-06-29
Codeshare flight, operated by Copa Airlines.(CM 301)
Daily 21:24 Panama City Tocumen (PTY) 23:39 Guayaquil (GYE)
KLM KL 3012 Non-stop Boeing 737-800 (738) 2:15 Effective 2025-06-30 through 2025-10-24
Codeshare flight, operated by Copa Airlines.(CM 301)
Daily 21:24 Panama City Tocumen (PTY) 23:41 Guayaquil (GYE)
KLM KL 3012 Non-stop Boeing 737-800 (738) 2:17 Effective 2025-10-25 through 2026-01-31
Codeshare flight, operated by Copa Airlines.(CM 301)
Tue-Sun 21:24 Panama City Tocumen (PTY) 23:37 Guayaquil (GYE)
KLM KL 3012 Non-stop Boeing 737-800 (738) 2:13 Effective from 2026-02-01
Codeshare flight, operated by Copa Airlines.(CM 301)
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All airlines flying from Panama City Tocumen (PTY) to Guayaquil (GYE).
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Select flight date:
FLIGHT SCHEDULE
Direct Flights:

Effective 2025-05-12 through 2025-05-16
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-05-17 through 2025-05-31
Mon
Tue
Wed
Thu
Fri
-
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective 2025-05-23 through 2025-05-30
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Operates only on 2025-06-01
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:13, non-stop
Boeing 737-700 (73G)

Effective 2025-06-02 through 2025-06-08
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective 2025-06-09 through 2025-06-23
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-06-10 through 2025-06-26
Mon
-
Tue
Wed
Thu
Fri
-
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective 2025-06-27 through 2025-06-29
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Operates only on 2025-06-30
Mon
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-07-01 through 2025-07-08
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Operates only on 2025-07-02
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:15, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-07-09 through 2025-08-10
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Effective 2025-08-11 through 2025-08-13
Mon
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:15, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-08-12 through 2025-08-21
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Effective 2025-08-20 through 2025-08-27
Mon
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:15, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-08-23 through 2025-08-31
Mon
-
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Effective 2025-09-01 through 2025-10-07
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Operates only on 2025-10-08
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:15, non-stop
Boeing 737-700 (73G)

Effective 2025-10-09 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:15, non-stop
Boeing 737-800 (738)

Operates only on 2025-10-26
Mon
-
Tue
-
Wed
-
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2025-10-27 through 2025-11-04
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2025-11-05 through 2025-11-12
Mon
-
Tue
-
Wed
Thu
Fri
-
Sat
-
Sun
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2025-11-07 through 2025-11-13
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2025-11-14 through 2025-11-19
Mon
-
Tue
-
Wed
Thu
-
Fri
Sat
-
Sun
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2025-11-15 through 2025-12-22
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
-
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2025-11-23 through 2025-12-24
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Operates only on 2025-12-23
Mon
-
Tue
Wed
-
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:17, non-stop
Boeing 737 MAX 8 (7M8)

Effective 2025-12-25 through 2026-01-08
Mon
Tue
Wed
-
Thu
Fri
-
Sat
Sun
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2025-12-26 through 2026-01-23
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:17, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-12-31 through 2026-01-07
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2026-01-10 through 2026-01-14
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
Sun
-
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2026-01-11 through 2026-01-29
Mon
Tue
Wed
-
Thu
Fri
-
Sat
Sun
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2026-01-21 through 2026-01-28
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:17, non-stop
Boeing 737-700 (73G)

Effective 2026-01-30 through 2026-01-31
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
Sun
-
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective 2026-02-01 through 2026-02-19
Mon
Tue
Wed
-
Thu
Fri
-
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective from 2026-02-04
Mon
-
Tue
-
Wed
Thu
-
Fri
-
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737-700 (73G)

Effective 2026-02-06 through 2026-02-13
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2026-02-20 through 2026-02-26
Mon
Tue
Wed
-
Thu
Fri
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective from 2026-02-27
Mon
-
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
-
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective from 2026-02-28
Mon
Tue
Wed
-
Thu
Fri
-
Sat
Sun
Duration: 2:13, non-stop
Boeing 737-800 (738)

Non-Direct Flights:

Valid until 2025-06-01
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
Duration: 6:15, 1-stop
Airbus A320 (320)

Effective from 2025-10-26
Mon
Tue
-
Wed
-
Thu
-
Fri
Sat
-
Sun
Duration: 5:50, 1-stop
Airbus A320 (320)

Direct Codeshare Flights:

Effective 2025-10-26 through 2026-01-31
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 213)
Duration: 2:17, non-stop
Boeing 737 MAX 9 (7M9)

Valid until 2025-06-30
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 213)
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Effective 2025-07-01 through 2025-10-25
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 213)
Duration: 2:15, non-stop
Boeing 737 MAX 9 (7M9)

Effective from 2026-02-01
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 213)
Duration: 2:13, non-stop
Boeing 737 MAX 9 (7M9)

Valid until 2025-06-29
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 301)
Duration: 2:13, non-stop
Boeing 737-800 (738)

Effective 2025-06-30 through 2025-10-24
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 301)
Duration: 2:15, non-stop
Boeing 737-800 (738)

Effective 2025-10-25 through 2026-01-31
Mon
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 301)
Duration: 2:17, non-stop
Boeing 737-800 (738)

Effective from 2026-02-01
Mon
-
Tue
Wed
Thu
Fri
Sat
Sun
Codeshare flight, operated by Copa Airlines. (CM 301)
Duration: 2:13, non-stop
Boeing 737-800 (738)
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  • An international route departing from Panama City Tocumen airport, Panama (PTY) and arriving at Guayaquil airport, Ecuador (GYE).
  • The flight distance is 776 miles, or 1249 km.
  • The timezone of both the departure and the arrival airports is UTC-5 . Current time at both airports is (loading...).
  • For direct flights, the flight time varies between 2:13 and 2:17.